BONESET

OTHER NAME(S):

Agueweed, Bois Perfolié, Crosswort, Eupatoire, Eupatoire Perfoliée, Eupatorio, Eupatorium perfoliatum, Feverwort, Herbe à Fi&egrave;vre, Herbe à Souder, Indian Sage, Sweating Plant, Teasel, Thoroughwort, Vegetable Antimony.<br/><br/>

Overview

Overview Information

Boneset is a plant. People use the dried leaf and flowers to make medicine.

Boneset is used to reduce fever, increase urine output, cause vomiting, and treat constipation.

Boneset is also used to treat influenza, swine flu, acute bronchitis, nasal inflammation, joint pain (rheumatism), fluid retention, dengue fever, and pneumonia; as a stimulant; and to cause sweating.

How does it work?

Boneset contains chemicals that might work like anti-cancermedications. It also might have some mild activity against bacteria.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Common cold. Early research suggests that taking a specific homeopathic product made from boneset (Eupatorium perfoliatum D2) reduces symptoms of the common cold similarly to aspirin.
  • Constipation.
  • Causing vomiting.
  • Fluid retention.
  • Aching muscles.
  • Reducing inflammation.
  • Stimulating the immune system.
  • Other conditions.
More evidence is needed to rate the effectiveness of boneset for these uses.

Side Effects

Side Effects & Safety

Boneset is POSSIBLY UNSAFE when taken by mouth in large amounts. Some plants that are related to boneset contain chemicals called pyrrolizidine alkaloids that can damage the liver. It is not known if boneset contains these chemicals.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Because boneset may contain liver-damaging chemicals called pyrrolizidine alkaloids, it is considered POSSIBLY UNSAFE. Don’t use it if you are pregnant or breast-feeding.

Allergy to ragweed and related plants: Boneset may cause an allergic reaction in people who are sensitive to plants in the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking boneset.

Liver disease: Boneset contains chemicals called hepatotoxic pyrrolizidine alkaloids (PAs). These chemicals might harm the liver, making existing liver disease worse.

Interactions

Interactions?

We currently have no information for BONESET Interactions.

Dosing

Dosing

The appropriate dose of boneset depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for boneset. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Gassinger, C. A., Wunstel, G., and Netter, P. [A controlled clinical trial for testing the efficacy of the homeopathic drug eupatorium perfoliatum D2 inthe treatment of common cold (author's transl)]. Arzneimittelforschung. 1981;31(4):732-736. View abstract.
  • Herz, W., Kalyanaraman, P. S., and Ramakrishnan, G. Sesquiterpene lactones of Eupatorium perfoliatum. J Org.Chem 6-24-1977;42(13):2264-2271. View abstract.
  • Wagner, H. and Jurcic, K. [Immunologic studies of plant combination preparations. In-vitro and in-vivo studies on the stimulation of phagocytosis]. Arzneimittelforschung. 1991;41(10):1072-1076. View abstract.
  • Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. View abstract.
  • Habtemariam S, Macpherson AM. Cytotoxicity and antibacterial activity of ethanol extract from leaves of a herbal drug, boneset (Eupatorium perfoliatum). Phytother Res 2000;14:575-7. . View abstract.
  • Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  • Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. View abstract.

More Resources for BONESET

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.