Amin, A., Alkaabi, A., Al Falasi, S., and Daoud, S. A. Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer. Cell Biol.Int 2005;29(8):687-694. View abstract.
Anuradha, C. V. and Ravikumar, P. Restoration on tissue antioxidants by fenugreek seeds (Trigonella Foenum Graecum) in alloxan-diabetic rats. Indian J Physiol Pharmacol 2001;45(4):408-420. View abstract.
Awadalla, M. Z., El Gedaily, A. M., El Shamy, A. E., and El Aziz, K. A. Studies on some Egyptian foods. Part 1: Biochemical and biological evaluation. Z.Ernahrungswiss. 1980;19(4):244-247. View abstract.
Belguith-Hadriche, O., Bouaziz, M., Jamoussi, K., El Feki, A., Sayadi, S., and Makni-Ayedi, F. Lipid-lowering and antioxidant effects of an ethyl acetate extract of fenugreek seeds in high-cholesterol-fed rats. J Agric.Food Chem 2-24-2010;58(4):2116-2122. View abstract.
Beutin, L. and Martin, A. Outbreak of Shiga toxin-producing Escherichia coli (STEC) O104:H4 infection in Germany causes a paradigm shift with regard to human pathogenicity of STEC strains. J Food Prot. 2012;75(2):408-418. View abstract.
Blanco, J. [Stx2a-producing enteroaggregative Escherichia coli O104:H4-ST678. Microbiological diagnostic already, for this and other STEC/VTEC serotypes!]. Enferm.Infecc.Microbiol.Clin. 2012;30(2):84-89. View abstract.
Dakam, W., Shang, J., Agbor, G., and Oben, J. Effects of sodium bicarbonate and albumin on the in vitro water-holding capacity and some physiological properties of Trigonella foenum graecum L. galactomannan in rats. J Med Food 2007;10(1):169-174. View abstract.
Daoud, K. M. The reserve polysaccharide of the seeds of fenugreek: its digestibility and its fate during germination. Biochem.J 1932;26(1):255-263. View abstract.
Devasena, T. and Menon, V. P. Fenugreek affects the activity of beta-glucuronidase and mucinase in the colon. Phytother Res 2003;17(9):1088-1091. View abstract.
Devasena, T. and Venugopal, Menon P. Fenugreek seeds modulate 1,2-dimethylhydrazine-induced hepatic oxidative stress during colon carcinogenesis. Ital.J Biochem. 2007;56(1):28-34. View abstract.
Dilsiz, N., Sahaboglu, A., Yildiz, M. Z., and Reichenbach, A. Protective effects of various antioxidants during ischemia-reperfusion in the rat retina. Graefes Arch Clin Exp.Ophthalmol. 2006;244(5):627-633. View abstract.
Gupta SK, Kalaiselvan V, Srivastava S, and et al. Inhibitory effect of Trigonella Foenum-Graecum on galactose induced cataracts in a rat model; in vitro and in vivo studies. Journal of Ophthalmic & Vision Research (J OPHTHALMIC VISION RES) 2009;4(4):213-219.
Haddad PS, Depot M, Settaf A, and et al. Comparative study on the medicinal plants most recommended by traditional practitioners in Morocco and Canada. Journal of Herbs, Spices & Medicinal Plants (J HERBS SPICES MEDICINAL PLANT) 2003;10(3):25-45.
Handa, T., Yamaguchi, K., Sono, Y., and Yazawa, K. Effects of fenugreek seed extract in obese mice fed a high-fat diet. Biosci.Biotechnol.Biochem. 2005;69(6):1186-1188. View abstract.
Hibasami, H., Moteki, H., Ishikawa, K., Katsuzaki, H., Imai, K., Yoshioka, K., Ishii, Y., and Komiya, T. Protodioscin isolated from fenugreek (Trigonella foenumgraecum L.) induces cell death and morphological change indicative of apoptosis in leukemic cell line H-60, but not in gastric cancer cell line KATO III. Int J Mol.Med 2003;11(1):23-26. View abstract.
Ikeuchi, M., Yamaguchi, K., Koyama, T., Sono, Y., and Yazawa, K. Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. J Nutr Sci Vitaminol.(Tokyo) 2006;52(4):287-292. View abstract.
Kochhar, A. and Nagi, M. Effect of supplementation of traditional medicinal plants on blood glucose in non-insulin-dependent diabetics: a pilot study. J Med Food 2005;8(4):545-549. View abstract.
Kuppu RK, Srivastava A, Krishnaswami CV, and et al. Hypoglycaemic and hypotriglyceridemic effects of 'methica churna' (Fenugreek). Antiseptic 1998;95:78-79.
Lakshminarayana, R., Aruna, G., Sangeetha, R. K., Bhaskar, N., Divakar, S., and Baskaran, V. Possible degradation/biotransformation of lutein in vitro and in vivo: isolation and structural elucidation of lutein metabolites by HPLC and LC-MS (atmospheric pressure chemical ionization). Free Radic.Biol.Med 10-1-2008;45(7):982-993. View abstract.
Lakshminarayana, R., Raju, M., Keshava Prakash, M. N., and Baskaran, V. Phospholipid, oleic acid micelles and dietary olive oil influence the lutein absorption and activity of antioxidant enzymes in rats. Lipids 2009;44(9):799-806. View abstract.
Laroubi, A., Touhami, M., Farouk, L., Zrara, I., Aboufatima, R., Benharref, A., and Chait, A. Prophylaxis effect of Trigonella foenum graecum L. seeds on renal stone formation in rats. Phytother Res 2007;21(10):921-925. View abstract.
Li, F., Fernandez, P. P., Rajendran, P., Hui, K. M., and Sethi, G. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Lett. 6-28-2010;292(2):197-207. View abstract.
Losso, J. N., Holliday, D. L., Finley, J. W., Martin, R. J., Rood, J. C., Yu, Y., and Greenway, F. L. Fenugreek bread: a treatment for diabetes mellitus. J Med Food 2009;12(5):1046-1049. View abstract.
Lu, F. R., Shen, L., Qin, Y., Gao, L., Li, H., and Dai, Y. Clinical observation on trigonella foenum-graecum L. total saponins in combination with sulfonylureas in the treatment of type 2 diabetes mellitus. Chin J Integr.Med 2008;14(1):56-60. View abstract.
Madar Z and Arad J. Effect of extracted fenugreek on post-prandial glucose levels in human diabetic subjects. Nutr Res 1989;9:691-692.
Madar, Z. New sources of dietary fibre. Int J Obes. 1987;11 Suppl 1:57-65. View abstract.
Mohammad, S., Taha, A., Akhtar, K., Bamezai, R. N., and Baquer, N. Z. In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats. Can J Physiol Pharmacol 2006;84(6):647-654. View abstract.
Mora, A., Herrrera, A., Lopez, C., Dahbi, G., Mamani, R., Pita, J. M., Alonso, M. P., Llovo, J., Bernardez, M. I., Blanco, J. E., Blanco, M., and Blanco, J. Characteristics of the Shiga-toxin-producing enteroaggregative Escherichia coli O104:H4 German outbreak strain and of STEC strains isolated in Spain. Int Microbiol. 2011;14(3):121-141. View abstract.
Murakami, T., Kishi, A., Matsuda, H., and Yoshikawa, M. Medicinal foodstuffs. XVII. Fenugreek seed. (3): structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonellafoenum-graecum L. Chem Pharm.Bull (Tokyo) 2000;48(7):994-1000. View abstract.
Nahas, R. and Moher, M. Complementary and alternative medicine for the treatment of type 2 diabetes. Can Fam.Physician 2009;55(6):591-596. View abstract.
Narender, T., Puri, A., Shweta, Khaliq, T., Saxena, R., Bhatia, G., and Chandra, R. 4-hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent. Bioorg.Med Chem Lett. 1-15-2006;16(2):293-296. View abstract.
O'Mahony, R., Al Khtheeri, H., Weerasekera, D., Fernando, N., Vaira, D., Holton, J., and Basset, C. Bactericidal and anti-adhesive properties of culinary and medicinal plants against Helicobacter pylori. World J Gastroenterol. 12-21-2005;11(47):7499-7507. View abstract.
Parildar, H., Serter, R., and Yesilada, E. Diabetes mellitus and phytotherapy in Turkey. J Pak.Med.Assoc. 2011;61(11):1116-1120. View abstract.
Parvizpur, A., Ahmadiani, A., and Kamalinejad, M. Probable role of spinal purinoceptors in the analgesic effect of Trigonella foenum (TFG) leaves extract. J Ethnopharmacol 3-8-2006;104(1-2):108-112. View abstract.
Raghuram TC, Sharma RD, Sivakumar B, and et al. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependent diabetic patients. Phytotherapy Research 1994;8(2):83-86.
Rai, A., Mohapatra, S. C., and Shukla, H. S. Correlates between vegetable consumption and gallbladder cancer. Eur J Cancer Prev. 2006;15(2):134-137. View abstract.
Ravikumar, P. and Anuradha, C. V. Effect of fenugreek seeds on blood lipid peroxidation and antioxidants in diabetic rats. Phytother Res 1999;13(3):197-201. View abstract.
Roberts, K. T. The potential of fenugreek (Trigonella foenum-graecum) as a functional food and nutraceutical and its effects on glycemia and lipidemia. J Med.Food 2011;14(12):1485-1489. View abstract.
Ruby, B. C., Gaskill, S. E., Slivka, D., and Harger, S. G. The addition of fenugreek extract (Trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise. Amino.Acids 2005;28(1):71-76. View abstract.
Sauvaire, Y., Ribes, G., Baccou, J. C., and Loubatieres-Mariani, M. M. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids 1991;26(3):191-197. View abstract.
Sebastian, K. S. and Thampan, R. V. Differential effects of soybean and fenugreek extracts on the growth of MCF-7 cells. Chem Biol.Interact. 11-20-2007;170(2):135-143. View abstract.
Shabbeer, S., Sobolewski, M., Anchoori, R. K., Kachhap, S., Hidalgo, M., Jimeno, A., Davidson, N., Carducci, M. A., and Khan, S. R. Fenugreek: a naturally occurring edible spice as an anticancer agent. Cancer Biol.Ther 2009;8(3):272-278. View abstract.
Sharma RD and Raghuram TC. Hypoglycaemic effect of fenugreek seeds in non-insulin dependent diabetic subjects. Nutr Res 1990;10:731-739.
Sharma RD, Sarkar A, Hazra DK, and et al. Toxicological evaluation of fenugreek seeds: a long term feeding experiment in diabetic patients. Phytother Res 1996;10(6):519-520.
Sharma RD, Sarkar DK, Hazra B, and et al. Hypolipidaemic effect of fenugreek seeds: a chronic study in non-insulin dependent diabetic patients. Phytother Res 1996;10:332-334.
Sharma RD. Effect of fenugreek seeds and leaves on blood glucose and serum insulin responses in human subjects. Nutr Res 1986;6:1353-1364.
Shojaii, A., Dabaghian, F. H., Goushegir, A., and Fard, M. A. Antidiabetic plants of Iran. Acta Med.Iran 2011;49(10):637-642. View abstract.
Slivka, D., Cuddy, J., Hailes, W., Harger, S., and Ruby, B. Glycogen resynthesis and exercise performance with the addition of fenugreek extract (4-hydroxyisoleucine) to post-exercise carbohydrate feeding. Amino.Acids 2008;35(2):439-444. View abstract.
Srichamroen, A., Thomson, A. B., Field, C. J., and Basu, T. K. In vitro intestinal glucose uptake is inhibited by galactomannan from Canadian fenugreek seed (Trigonella foenum graecum L) in genetically lean and obese rats. Nutr Res 2009;29(1):49-54. View abstract.
Srinivasan, K. Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts. Int.J Food Sci.Nutr. 2005;56(6):399-414. View abstract.
Srinivasan, S., Koduru, S., Kumar, R., Venguswamy, G., Kyprianou, N., and Damodaran, C. Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells. Int J Cancer 8-15-2009;125(4):961-967. View abstract.
Stark, A. and Madar, Z. The effect of an ethanol extract derived from fenugreek (Trigonella foenum-graecum) on bile acid absorption and cholesterol levels in rats. Br J Nutr 1993;69(1):277-287. View abstract.
Taylor, W. G., Zulyniak, H. J., Richards, K. W., Acharya, S. N., Bittman, S., and Elder, J. L. Variation in diosgenin levels among 10 accessions of fenugreek seeds produced in western Canada. J Agric.Food Chem 10-9-2002;50(21):5994-5997. View abstract.
Thirunavukkarasu V and Anuradha CV. Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats. Journal of Herbs, Spices & Medicinal Plants (J HERBS SPICES MEDICINAL PLANT) 2006;12(3):13-25.
Thirunavukkarasu, V., Anuradha, C. V., and Viswanathan, P. Protective effect of fenugreek (Trigonella foenum graecum) seeds in experimental ethanol toxicity. Phytother Res 2003;17(7):737-743. View abstract.
Trivedi, P. D., Pundarikakshudu, K., Rathnam, S., and Shah, K. S. A validated quantitative thin-layer chromatographic method for estimation of diosgenin in various plant samples, extract, and market formulation. J AOAC Int 2007;90(2):358-363. View abstract.
Vijayakumar, M. V., Pandey, V., Mishra, G. C., and Bhat, M. K. Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor. Obesity.(Silver.Spring) 2010;18(4):667-674. View abstract.
Vijayakumar, M. V., Singh, S., Chhipa, R. R., and Bhat, M. K. The hypoglycaemic activity of fenugreek seed extract is mediated through the stimulation of an insulin signalling pathway. Br J Pharmacol 2005;146(1):41-48. View abstract.
Vyas, S., Agrawal, R. P., Solanki, P., and Trivedi, P. Analgesic and anti-inflammatory activities of Trigonella foenum-graecum (seed) extract. Acta Pol.Pharm. 2008;65(4):473-476. View abstract.
Yoshinari, O. and Igarashi, K. Anti-diabetic effect of trigonelline and nicotinic acid, on KK-A(y) mice. Curr Med Chem 2010;17(20):2196-2202. View abstract.
Zhao, H. Q., Qu, Y., Wang, X. Y., Lu, X. Y., Zhang, X. H., and Hattori, M. [Determination of trigonelline by HPLC and study on its pharmacokinetics]. Yao Xue.Xue.Bao. 2003;38(4):279-282. View abstract.
Zhao, H. Q., Qu, Y., Wang, X. Y., Zhang, H. J., Li, F. M., and Masao, H. [Determination of trigonelline in Trigonella foenum-graecum by HPLC]. Zhongguo Zhong.Yao Za Zhi. 2002;27(3):194-196. View abstract.
Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8. View abstract.
Ahsan SK, Tariq M, Ageel AM, et al. Effect of Trigonella foenum-graecum and Ammi majus on calcium oxalate urolithiasis in rats. J Ethnopharmacol 1989;26:249-54. View abstract.
Al-Jenoobi FI, Ahad A, Mahrous GM, Al-Mohizea AM, AlKharfy KM, Al-Suwayeh SA. Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs. Pharm Biol 2015;53(2):296-300. View abstract.
Al-khalisy MHH. Treatment of Men Infertility using Low doses of Fenugreek Oil Extract. Advances Life Sci Technol 2015;29:13-16.
Al-Mohizea AM, Ahad A, El-Maghraby GM, et al. Effects of Nigella sativa, Lepidium sativum and Trigonella foenum-graecum on sildenafil disposition in beagle dogs. Eur J Drug Metab Pharmacokinet. 2015;40(2):219-24. View abstract.
Alkharfy K, Jan B, Alotaibi K, et al. Clopidogrel-herb Interactions: A Pharmacokinetic and Pharmacodynamic Assessment in a Rat Model. Curr Drug Metab 2021;22(12):969-977. View abstract.
Alkharfy KM, Al-Jenoobi FI, Al-Mohizea AM, et al. Effects of Lepidium sativum, Nigella sativa and Trigonella foenum-graceum on phenytoin pharmacokinetics in beagle dogs. Phytother Res. 2013;27(12):1800-4. View abstract.
Amini MR, Payandeh N, Sheikhhossein F, et al. The Effects of Fenugreek Seed Consumption on Blood Pressure: A Systematic Review and Meta-analysis of Randomized Controlled Trials. High Blood Press Cardiovasc Prev 2023;30(2):123-133. View abstract.
Arafa MH, Mohammad NS, Atteia HH. Fenugreek seed powder mitigates cadmium-induced testicular damage and hepatotoxicity in male rats. Exp Toxicol Pathol. 2014 Sep;66(7):293-300. View abstract.
Askarpour M, Alami F, Campbell MS, Venkatakrishnan K, Hadi A, Ghaedi E. Effect of fenugreek supplementation on blood lipids and body weight: a systematic review and meta-analysis of randomized controlled trials. J Ethnopharmacol 2020;253:112538. View abstract.
Aswar U, Bodhankar SL, Mohan V, Thakurdesai PA. Effect of furostanol glycosides from Trigonella foenum-graecum on the reproductive system of male albino rats. Phytother Res. 2010 Oct;24(10):1482-8. View abstract.
Bartley GB, Hilty MD, Andreson BD, et al. "Maple-syrup" urine odor due to fenugreek ingestion. N Engl J Med 1981;305:467. View abstract.
Bhardwaj PK, Dasgupta DJ, Prashar BS, Kaushal SS. Control of hyperglycaemia and hyperlipidaemia by plant product. J Assoc Physicians India 1994;42:33-5. View abstract.
Bin Jardan YA, Ahad A, Raish M, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. Effects of garden cress, fenugreek and black seed on the pharmacodynamics of metoprolol: an herb-drug interaction study in rats with hypertension. Pharm Biol 2021;59(1):1088-1097. View abstract.
Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty Acids 1997;56:379-84. View abstract.
Broca C, Manteghetti M, Gross R, et al. 4-Hydroxyisoleucine: effects of synthetic and natural analogues on insulin secretion. Eur J Pharmacol 2000;390:339-45. View abstract.
Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. View abstract.
Che CT, Douglas L, Liem J. Case reports of peanut-fenugreek and cashew-sumac cross-reactivity. J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2):510-511. View abstract.
Chevassus H, Gaillard JB, Farret A, et al. A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. Eur J Clin Pharmacol 2010;66(5):449-55. View abstract.
Chevassus H, Molinier N, Costa F, et al. A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers. Eur J Clin Pharmacol 2009;65(12):1175-8. View abstract.
Correia AGDS, Alencar MB, Dos Santos AN, et al. Effect of saffron and fenugreek on lowering blood glucose: A systematic review with meta-analysis. Phytother Res 2023. View abstract.
DiSilvestro RA, Verbruggen MA, Offutt EJ. Anti-heartburn effects of a fenugreek fiber product. Phytother Res 2011;25:88-91. View abstract.
Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: https://www.ars-grin.gov/duke/.
Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
Faeste CK, Namork E, Lindvik H. Allergenicity and antigenicity of fenugreek (Trigonella foenum-graecum) proteins in foods. J Allergy Clin Immunol 2009;123(1):187-94. View abstract.
Fakhr L, Chehregosha F, Zarezadeh M, Chaboksafar M, Tarighat-Esfanjani A. Effects of fenugreek supplementation on the components of metabolic syndrome: A systematic review and dose-response meta-analysis of randomized clinical trials. Pharmacol Res 2023;187:106594. View abstract.
Flammang AM, Cifone MA, Erexson GL, Stankowski LF Jr. Genotoxicity testing of a fenugreek extract. Food Chem Toxicol 2004;42:1769-75. View abstract.
Florentin M, Liberopoulos E, Elisaf MS, Tsimihodimos V. No effect of fenugreek, bergamot and olive leaf extract on glucose homeostasis in patients with prediabetes: a randomized double-blind placebo-controlled study. Arch Med Sci Atheroscler Dis. 2019;4:e162-e166. View abstract.
Foroumandi E, Javan R, Moayed L, et al. The effects of fenugreek seed extract supplementation in patients with Alzheimer's disease: A randomized, double-blind, placebo-controlled trial. Phytother Res 2023;37(1):285-294. View abstract.
Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. View abstract.
Geberemeskel GA, Debebe YG, Nguse NA. Antidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. J Diabetes Res. 2019;2019:8507453. View abstract.
Goh J, Menke W, Herrick LP, et al. Examination of Curcumin and Fenugreek Soluble Fiber Supplementation on Submaximal and Maximal Aerobic Performance Indices. J Funct Morphol Kinesiol 2020;5(2):34. View abstract.
Gong J, Fang K, Dong H, Wang D, Hu M, Lu F. Effect of fenugreek on hyperglycaemia and hyperlipidemia in diabetes and prediabetes: A meta-analysis. J Ethnopharmacol. 2016 Dec 24;194:260-268. View abstract.
Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61. View abstract.
Hakimi S, Delazar A, Mobaraki-Asl N, Amiri P, Tavassoli H, Safari M. Comparison of the effects of fenugreek vaginal cream and ultra low-dose estrogen on atrophic vaginitis. Curr Drug Deliv 2020. Online ahead of print. View abstract.
Hamden K, Jaouadi B, Carreau S, Aouidet A, El-Fazaa S, Gharbi N, Elfeki A. Potential protective effect on key steroidogenesis and metabolic enzymes and sperm abnormalities by fenugreek steroids in testis and epididymis of surviving diabetic rats. Arch Physiol Biochem. 2010 Jul;116(3):146-55. View abstract.
Hannan JM, Rokeya B, Faruque O, et al. Effect of soluble dietary fibre fraction of Trigonella foenum graecum on glycemic, insulinemic, lipidemic and platelet aggregation status of Type 2 diabetic model rats. J Ethnopharmacol 2003;88:73-7. View abstract.
Hassani SS, Fallahi Arezodar F, Esmaeili SS, Gholami-Fesharaki M. Effect of Fenugreek Use on Fasting Blood Glucose, Glycosylated Hemoglobin, Body Mass Index, Waist Circumference, Blood Pressure and Quality of Life in Patients with Type 2 Diabetes Mellitus: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trials. Galen Med J 2019;8:e1432. View abstract.
Hassanzadeh Bashtian M, Emami SA, Mousavifar N, Esmaily HA, Mahmoudi M, Mohammad Poor AH. Evaluation of Fenugreek (Trigonella foenum-graceum L.), Effects Seeds Extract on Insulin Resistance in Women with Polycystic Ovarian Syndrome. Iran J Pharm Res 2013;12(2):475-81. View abstract.
Hausenblas HA, Conway KL, Coyle KRM, et al. Efficacy of fenugreek seed extract on men's psychological and physical health: a randomized placebo-controlled double-blind clinical trial. J Complement Integr Med 2020. Online ahead of print. View abstract.
Heshmat-Ghahdarijani K, Mashayekhiasl N, Amerizadeh A, Teimouri Jervekani Z, Sadeghi M. Effect of fenugreek consumption on serum lipid profile: a systematic review and meta-analysis. Phytother Res 2020. Online ahead of print. View abstract.
Kassaian N, Azadbakht L, Forghani B, Amini M. Effect of fenugreek seeds on blood glucose and lipid profiles in type 2 diabetic patients. Int J Vitam Nutr Res 2009;79(1):34-9. View abstract.
Khan TM, Wu DB, Dolzhenko AV. Effectiveness of fenugreek as a galactagogue: A network meta-analysis. Phytother Res. 2018 Mar;32(3):402-412. View abstract.
Khanna A, John F, Das S, et al. Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double-blinded, placebo-controlled study. J Food Biochem. 2020;44(12):e13507. View abstract.
Khodamoradi K, Khosropanah MH, Ayati Z, et al. The Effects of Fenugreek on Cardiometabolic Risk Factors in Adults: A Systematic Review and Meta-analysis. Complement Ther Med. 2020;52:102416. View abstract.
King LA, Nogareda F, Weill FX, Mariani-Kurkdjian P, Loukiadis E, Gault G, Jourdan-DaSilva N, Bingen E, Macé M, Thevenot D, Ong N, Castor C, Noël H, Van Cauteren D, Charron M, Vaillant V, Aldabe B, Goulet V, Delmas G, Couturier E, Le Strat Y, Combe C, Delmas Y, Terrier F, Vendrely B, Rolland P, de Valk H. Outbreak of Shiga toxin-producing Escherichia coli O104:H4 associated with organic fenugreek sprouts, France, June 2011. Clin Infect Dis 2012;54(11):1588-94. View abstract.
Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. View abstract.
Madar Z, Abel R, Samish S, Arad J. Glucose-lowering effect of fenugreek in non-insulin dependent diabetics. Eur J Clin Nutr 1988;42:51-4. View abstract.
Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74. View abstract.
Mansoori A, Hosseini S, Zilaee M, Hormoznejad R, Fathi M. Effect of fenugreek extract supplement on testosterone levels in male: a meta-analysis of clinical trials. Phytother Res 2020;34(7):1550-5. View abstract.
Mathern JR, Raatz SK, Thomas W, Slavin JL. Effect of fenugreek fiber on satiety, blood glucose and insulin response and energy intake in obese subjects. Phytother Res 2009;23(11):1543-8. View abstract.
Mazalzadeh F, Hekmat K, Namjouyan F, Saki A. Effect of Trigonella foenum (fenugreek) vaginal cream on vaginal atrophy in postmenopausal women. J Family Med Prim Care. 2020;9(6):2714-2719. View abstract.
Nathan J, Panjwani S, Mohan V, Joshi V, Thakurdesai PA. Efficacy and safety of standardized extract of Trigonella foenum-graecum L seeds as an adjuvant tocL-Dopa in the management of patients with Parkinson's disease. Phytother Res 2014;28(2):172-8. View abstract.
Neelakantan N, Narayanan M, de Souza RJ, van Dam RM. Effect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials. Nutr J 2014;13:7. View abstract.
Ouzir M, El Bairi K, Amzazi S. Toxicological properties of fenugreek (Trigonella foenum graecum). Food Chem Toxicol. 2016 Oct;96:145-54. View abstract.
Palacios AM, Cardel MI, Parker E, et al. Effectiveness of lactation cookies on human milk production rates: a randomized controlled trial. Am J Clin Nutr 2023;117(5):1035-1042. View abstract.
Pathak P, Srivastava S, Grover S. Development of food products based on millets, legumes and fenugreek seeds and their suitability in the diabetic diet. Int J Food Sci Nutr 2000;51:409-14.. View abstract.
Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. View abstract.
Pickering E, Steels E, Rao A, Steadman KJ. An Exploratory Study of the Safety and Efficacy of a Trigonella foenum-graecum Seed Extract in Early Glucose Dysregulation: A Double-Blind Randomized Placebo-Controlled Trial. Pharmaceutics 2022;14(11):2453. View abstract.
Rao A, Grant R. The effect of Trigonella foenum-graecum extract on prostate-specific antigen, and prostate function in otherwise healthy men with benign prostate hyperplasia. Phytother Res. 2019. View abstract.
Rao A, Steels E, Beccaria G, Inder WJ, Vitetta L. Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Phytother Res. 2015 Aug;29(8):1123-30. View abstract.
Rao A, Steels E, Inder WJ, Abraham S, Vitetta L. Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study. Aging Male. 2016 Jun;19(2):134-42. View abstract.
Reeder C, Legrand A, O'Connor-Von SK. The Effect of Fenugreek on Milk Production and Prolactin Levels in Mothers of Preterm Infants. Clinical Lactation 2013;4(4):159-165.
Sankhwar P, Jaiswar SP, Yadav S, et al. Beneficial Effects of a Novel Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst®) in Women with Polycystic Ovary Syndrome (PCOS): A Follow-up Compliance Clinical Investigation. J Am Nutr Assoc 2022. View abstract.
Sankhwar SN, Kumar P, Bagchi M, Rungta M, Bagchi D. Safety and Efficacy of Furosap®, a Patented Trigonella foenum-graecum Seed Extract, in Boosting Testosterone Level, Reproductive Health and Mood Alleviation in Male Volunteers. J Am Coll Nutr 2021. View abstract.
Selmi S, Alimi D, Rtibi K, et al. Gastroprotective and Antioxidant Properties of Trigonella foenum graecum Seeds Aqueous Extract (Fenugreek) and Omeprazole Against Ethanol-Induced Peptic Ulcer. J Med Food 2022;25(5):513-522. View abstract.
Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. View abstract.
Shabil M, Bushi G, Bodige PK, et al. Effect of Fenugreek on Hyperglycemia: A Systematic Review and Meta-Analysis. Medicina (Kaunas) 2023;59(2):248. View abstract.
Sharma RD, Raghuram TC, Dayasagar Rao V. Hypolipidaemic effect of fenugreek seeds. A clinical study. Phytother Res 1991;3(5):145-7.
Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6. View abstract.
Sharma RD, Sarkar DK, Hazra B, et al. Hypolipidaemic effect of fenugreek seeds: a chronic study in non-insulin dependent diabetic patients. Phytother Res 1996;10:332-4.
Singh A, Gainder S, Banerjee P, et al. Efficacy of a Proprietary Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst®) in Women with Polycystic Ovary Syndrome (PCOS): a Randomized, Double-Blind, Placebo-Controlled Study. J Am Nutr Assoc 2022. View abstract.
Singh RB, Niaz MA, Rastogi V, et al. Hypolipidemic and antioxidant effects of fenugreek seeds and triphala as adjuncts to dietary therapy in patients with mild to moderate hypercholesterolemia. Perfusion (Munich) 1998;11:124-30.
Sowmya P, Rajyalakshmi P. Hypocholesterolemic effect of germinated fenugreek seeds in human subjects. Plant Foods Hum Nutr 1999;53:359-65.. View abstract.
Steels E, Rao A, Vitetta L. Physiological aspects of male libido enhanced by standardized Trigonella foenum-graecum extract and mineral formulation. Phytother Res. 2011 Sep;25(9):1294-300. View abstract.
Suksomboon N, Poolsup N, Boonkaew S, Suthisisang CC. Meta-analysis of the effect of herbal supplement on glycemic control in type 2 diabetes. J Ethnopharmacol 2011;137(3):1328-1333. View abstract.
Swafford S, Berens P. Effect of fenugreek on breast milk volume. Abstract presented at: 5th International Meeting of the Academy of Breastfeeding Medicine; September 11-13,2000, Tucson, Arizona.
Swaroop A, Jaipuriar AS, Gupta SK, Bagchi M, Kumar P, Preuss HG, Bagchi D. Efficacy of a Novel Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst) in Polycystic Ovary Syndrome (PCOS). Int J Med Sci. 2015 Oct 3;12(10):825-31. View abstract.
Turkyilmaz C, Onal E, Hirfanoglu IM, et al. The effect of galactagogue herbal tea on breast milk production and short-term catch-up of birth weight in the first week of life. J Altern Complement Med 2011;17(2):139-42. View abstract.
Wankhede S, Mohan V, Thakurdesai P. Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: a randomized controlled pilot study, J. Sport and Health Sci. 2016. 6: 176-182.
Wilborn C, Bushey B, Poole C, et al. Effects of Torabolic supplementation on strength and body composition during an 8-week resistance training program. J Int Soc Sports Nutr 2008;5(1):11.
Wilborn C, Taylor L, Poole C, et al. Effects of a purported aromatase and 5alpha-reductase inhibitor on hormone profiles in college-age men. Int J Sport Nutr Exerc Metab 2010;20(6):457-65. View abstract.
Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9.
Younesy S, Amiraliakbari S, Esmaeili S, Alavimajd H, Nouraei S. Effects of fenugreek seed on the severity and systemic symptoms of dysmenorrhea. J Reprod Infertil 2014;15(1):41-8. View abstract.
Abdel-Barry, J. A., Abdel-Hassan, I. A., Jawad, A. M., and al Hakiem, M. H. Hypoglycaemic effect of aqueous extract of the leaves of Trigonella foenum-graecum in healthy volunteers. East Mediterr.Health J 2000;6(1):83-88. View abstract.
Ahmadiani, A., Javan, M., Semnanian, S., Barat, E., and Kamalinejad, M. Anti-inflammatory and antipyretic effects of Trigonella foenum-graecum leaves extract in the rat. J Ethnopharmacol 2001;75(2-3):283-286. View abstract.