While rose hip is often considered a good source of vitamin C, the processing and drying of the plant actually destroys most of it. Besides vitamin C, other natural chemicals found in rose hip may be helpful for a variety of health conditions.
People use rose hip for osteoarthritis and pain after surgery. It is also used for many other conditions, but there is no good scientific evidence to support these other uses.
Uses & Effectiveness ?
Possibly Effective for
- Osteoarthritis. Taking rose hip by mouth, alone or with other natural medicines, can reduce pain and stiffness and improve function in people with osteoarthritis.
- Pain after surgery. Taking a single dose of rose hip extract by mouth right before a C-section helps to reduce pain and the need for pain medications after surgery.
When applied to the skin: There isn't enough reliable information to know if rose hip is safe or what the side effects might be.
Special Precautions and Warnings
Kidney stones: In large doses, rose hip might increase the chance of getting kidney stones. This is due to the vitamin C in rose hip.
Aluminum interacts with ROSE HIP
Aluminum is found in most antacids. Rose hips contain vitamin C. Vitamin C can increase how much aluminum the body absorbs. But it isn't clear if this interaction is a big concern. Take rose hip two hours before or four hours after antacids.
Estrogens interacts with ROSE HIP
Rose hip contains a large amount of vitamin C. Vitamin C can increase how much estrogen the body absorbs. Taking rose hip along with estrogen can increase the effects and side effects of estrogens.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Fluphenazine (Prolixin) interacts with ROSE HIP
Rose hip contains vitamin C. Large amounts of vitamin C might increase how quickly the body gets rid of fluphenazine (Prolixin). Taking rose hip along with fluphenazine (Prolixin) might decrease the effectiveness of fluphenazine (Prolixin).
Warfarin (Coumadin) interacts with ROSE HIP
Warfarin (Coumadin) is used to slow blood clotting. Rose hip contains vitamin C. Large amounts of vitamin C might decrease the effectiveness of warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the risk of clotting. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.
Lithium interacts with ROSE HIP
Rose hip might have an effect like a water pill or "diuretic." Taking rose hip might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.
Be cautious with this combination
Aspirin interacts with ROSE HIP
The body breaks down aspirin to get rid of it. Rose hip contains large amounts of vitamin C. Large amounts of vitamin C might decrease the breakdown of aspirin. Taking large amount of rose hip along with aspirin might increase the effects and side effects of aspirin. Do not take large amounts of vitamin C if you take large amounts of aspirin.
Choline Magnesium Trisalicylate (Trilisate) interacts with ROSE HIP
Rose hip contains vitamin C. Vitamin C might decrease how quickly the body gets rid of choline magnesium trisalicylate (Trilisate). But it is not clear if this interaction is a big concern.
Salsalate (Disalcid) interacts with ROSE HIP
Rose hip contains vitamin C. Vitamin C might decrease how quickly the body gets rid of salsalate (Disalcid). Taking rose hip along with salsalate (Disalcid) might increase the effects and side effects of salsalate.
Be watchful with this combination
Itai T, Amayasu H, Kuribayashi M, and et al. Psychological effects of aromatherapy on chronic hemodialysis patients. Psychiatry Clin Neurosci 2000;54(4):393-397. View abstract.
Jager W, Buchbauer G, Jirovetz L, and et al. Percutaneous absorption of lavender oil from massage oil. J Soc Cosmet Chem 1992;43:49-54.
Jimbo, D., Kimura, Y., Taniguchi, M., Inoue, M., and Urakami, K. Effect of aromatherapy on patients with Alzheimer's disease. Psychogeriatrics. 2009;9(4):173-179. View abstract.
Jones, C. The efficacy of lavender oil on perineal trauma: a review of the evidence. Complement Ther Clin Pract. 2011;17(4):215-220. View abstract.
Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Efficacy and safety of silexan, a new, orally administered lavender oil preparation, in subthreshold anxiety disorder - evidence from clinical trials. Wien Med Wochenschr. 2010;160(21-22):547-556. View abstract.
Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, placebo controlled trial. Int Clin Psychopharmacol. 2010;25(5):277-287. View abstract.
Kim, M. J., Nam, E. S., and Paik, S. I. [The effects of aromatherapy on pain, depression, and life satisfaction of arthritis patients]. Taehan Kanho.Hakhoe.Chi 2005;35(1):186-194. View abstract.
Basim, E. and Basim, H. Antibacterial activity of Rosa damascena essential oil. Fitoterapia 2003;74(4):394-396. View abstract.
Biswas, N. R., Gupta, S. K., Das, G. K., Kumar, N., Mongre, P. K., Haldar, D., and Beri, S. Evaluation of Ophthacare eye drops--a herbal formulation in the management of various ophthalmic disorders. Phytother.Res. 2001;15(7):618-620. View abstract.
Cho, E. J., Yokozawa, T., Rhyu, D. Y., Kim, S. C., Shibahara, N., and Park, J. C. Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. Phytomedicine. 2003;10(6-7):544-551. View abstract.
Chrubasik, C., Duke, R. K., and Chrubasik, S. The evidence for clinical efficacy of rose hip and seed: a systematic review. Phytother Res 2006;20(1):1-3. View abstract.
Daels-Rakotoarison, D. A., Gressier, B., Trotin, F., Brunet, C., Luyckx, M., Dine, T., Bailleul, F., Cazin, M., and Cazin, J. C. Effects of Rosa canina fruit extract on neutrophil respiratory burst. Phytother.Res. 2002;16(2):157-161. View abstract.
Dushkin, M. I., Zykov, A. A., and Pivovarova, E. N. [The effect of natural polyphenol compounds on the oxidative modification of low-density lipoproteins]. Biull.Eksp.Biol Med 1993;116(10):393-395. View abstract.
Hornero-Mendez, D. and Minguez-Mosquera, M. I. Carotenoid pigments in Rosa mosqueta hips, an alternative carotenoid source for foods. J Agric Food Chem 2000;48(3):825-828. View abstract.
Janse, van Rensburg, Erasmus, E., Loots, D. T., Oosthuizen, W., Jerling, J. C., Kruger, H. S., Louw, R., Brits, M., and van der Westhuizen, F. H. Rosa roxburghii supplementation in a controlled feeding study increases plasma antioxidant capacity and glutathione redox state. Eur J Nutr 2005;44(7):452-457. View abstract.
Kumarasamy, Y., Cox, P. J., Jaspars, M., Nahar, L., and Sarker, S. D. Screening seeds of Scottish plants for antibacterial activity. J Ethnopharmacol 2002;83(1-2):73-77. View abstract.
Larsen, E., Kharazmi, A., Christensen, L. P., and Christensen, S. B. An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro. J.Nat.Prod. 2003;66(7):994-995. View abstract.
Ma, Y. X., Zhu, Y., Wang, C. F., Wang, Z. S., Chen, S. Y., Shen, M. H., Gan, J. M., Zhang, J. G., Gu, Q., and He, L. The aging retarding effect of 'Long-Life CiLi'. Mech.Ageing Dev 1997;96(1-3):171-180. View abstract.
Moreno Gimenez, J. C., Bueno, J., Navas, J., and Camacho, F. [Treatment of skin ulcer using oil of mosqueta rose]. Med Cutan.Ibero.Lat.Am 1990;18(1):63-66. View abstract.
Rein, E., Kharazmi, A., and Winther, K. A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trial. Phytomedicine. 2004;11(5):383-391. View abstract.
Rein, E., Kharazmi, A., Thamsborg, G., and Winther, K. Herbal remedy made from a subspecies of rose-hip Rosa canina reduces symptoms of knee and hip osteoarthritis. Osteoarthr Cartil 2004;12(Suppl 2):80.
Rossnagel, K. and Willich, S. N. [Value of complementary medicine exemplified by rose-hips]. Gesundheitswesen 2001;63(6):412-416. View abstract.
Shabykin, G. P. and Godorazhi, A. I. [A polyvitamin preparation of fat-soluble vitamins (carotolin) and rose hip oil in the treatment of certain dermatoses]. Vestn.Dermatol.Venerol. 1967;41(4):71-73. View abstract.
Shiota, S., Shimizu, M., Mizusima, T., Ito, H., Hatano, T., Yoshida, T., and Tsuchiya, T. Restoration of effectiveness of beta-lactams on methicillin-resistant Staphylococcus aureus by tellimagrandin I from rose red. FEMS Microbiol.Lett 4-15-2000;185(2):135-138. View abstract.
Teng, C. M., Kang, Y. F., Chang, Y. L., Ko, F. N., Yang, S. C., and Hsu, F. L. ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb. Thromb.Haemost. 1997;77(3):555-561. View abstract.
Trovato, A., Monforte, M. T., Forestieri, A. M., and Pizzimenti, F. In vitro anti-mycotic activity of some medicinal plants containing flavonoids. Boll Chim Farm 2000;139(5):225-227. View abstract.
Venkatesh, R. P., Ramaesh, K., and Browne, B. Rose-hip keratitis. Eye 2005;19(5):595-596. View abstract.
Warholm, O., Skaar, S., Hedman, E., Molmen, H. M., and Eik, L. The effects of a standardized herbal remedy ade from a subtype of Rosa canina in patients with osteoarthritis: a double-blind, randomized, placebo-controlled clinical trial. Curr Ther Res 2003;64(1):21-31.
Winther, K. and Kharazmi, A. A powder prepared from seeds and shells of subtype of rose-hip Rosa canina reduces pain in patients with osteoarthritis of the hand - a double blind, placebo-controlled study. Osteoarthr Cartil 2004;12(Suppl 2):145.
Winther, K., Apel, K., and Thamsborg, G. A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial. Scand J Rheumatol. 2005;34(4):302-308. View abstract.
Andersson U, Berger K, Hogberg A, et al. Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons. Eur J Clin Nutr 2012;66:585-90. View abstract.
Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516. View abstract.
Bani S, Hasanpour S, Mousavi Z, Mostafa Garehbaghi P, Gojazadeh M. The effect of Rosa damascena extract on primary dysmenorrhea: A double-blind cross-over clinical trial. Iran Red Crescent Med J. 2014;16(1):e14643. View abstract.
Bottari A, Belcaro G, Ledda A, et al. Lady Prelox improves sexual function in generally healthy women of reproductive age. Minerva Ginecol 2013;65(4):435-44. View abstract.
Cesarone MR, Belcaro G, Scipione C, et al. Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox®. Minerva Ginecol. 2019;71(6):434-41. View abstract.
Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. View abstract.
Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. View abstract.
Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: https://www.nap.edu/books/0309069351/html/.
Fresz T, Nagy E, Hilbert A, Tomcsanyi J. The role of flavonoids in false positive digoxin assays caused by the consumption of hibiscus flower and rose hip tea. Int J Cardiol 2014;171(2):273-4. View abstract.
García Hernández JÁ, Madera González D, Padilla Castillo M, Figueras Falcón T. Use of a specific anti-stretch mark cream for preventing or reducing the severity of striae gravidarum. Randomized, double-blind, controlled trial. Int J Cosmet Sci. 2013;35(3):233-7. View abstract.
Han SH, Hur MH, Buckle J, et al. Effect of aromatherapy on symptoms of dysmenorrhea in college students: A randomized placebo-controlled clinical trial. J Altern Complement Med 2006;12(6):535-41. View abstract.
Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. View abstract.
Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. View abstract.
Jiang K, Tang K, Liu H, Xu H, Ye Z, Chen Z. Ascorbic acid supplements and kidney stones incidence among men and women: a systematic review and meta-analysis. Urol J. 2019;16(2):115-120. View abstract.
Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8. View abstract.
Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. View abstract.
Mármol I, Sánchez-de-Diego C, Jiménez-Moreno N, Ancín-Azpilicueta C, Rodríguez-Yoldi MJ. Therapeutic applications of rose hips from different Rosa species. Int J Mol Sci. 2017;18(6):1137. View abstract.
Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. View abstract.
Moré M, Gruenwald J, Pohl U, Uebelhack R. A Rosa canina - urtica dioica - harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study. Planta Med 2017;83(18):1384-91. View abstract.
Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503. View abstract.
Mostafa-Gharabaghi P, Delazar A, Gharabaghi MM, Shobeiri MJ, Khaki A. The view of cesarean pain after preemptive use of Rosa damascena extract in women with elective cesarean section. World Sci J. 2013;4:226-35.
Oprica L, Bucsa C, Zamfiranche MM. Ascorbic acid content of rose hip fruit depending on altitude. Iran J Public Health 2015;44(1):138-9. View abstract.
Phetcharat L, Wongsuphasawat K, Winther K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin Interv Aging. 2015;10:1849-56. View abstract.
Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. View abstract.
Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. View abstract.
Seifi M, Abbasalizadeh S, Mohammad-Alizadeh-Charandabi S, Khodaie L, Mirghafourvand M. The effect of Rosa (L. Rosa canina) on the incidence of urinary tract infection in the puerperium: a randomized placebo-controlled trial. Phytother Res 2018;32(1):76-83. View abstract.
Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. View abstract.
Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol 2004;15:3225-32. View abstract.
Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. View abstract.
Van Steirteghem AC, Robertson EA, Young DS. Influence of large doses of ascorbic acid on laboratory test results. Clin Chem. 1978;24(1):54-7. View abstract.
Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. View abstract.
Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. View abstract.
Willich SN, Rossnagel K, Roll S, et al. Rose hip herbal remedy in patients wth rheumatoid arthritis - a randomised controlled trial. Phytomedicine 2010;17:87-93. View abstract.
Young DS. Effects of Drugs on Clinical Laboratory Tests 4th ed. Washington: AACC Press, 1995.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
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