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Hypothyroidism - Exams and Tests

A thorough medical history and physical exam are the first steps in diagnosing hypothyroidism or mild (subclinical) hypothyroidism. If the results lead your doctor to suspect you have hypothyroidism or subclinical hypothyroidism, you will have tests to confirm the diagnosis.

Blood tests are always used to confirm a diagnosis of hypothyroidism or mild hypothyroidism. The tests used most often are:

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If the above tests are not normal, antithyroid antibody tests may determine whether you have the autoimmune disease Hashimoto's thyroiditis, in which the body's defense system attacks the thyroid gland.

In rare cases, a thyroid ultrasound may be used to evaluate a thyroid gland that during a physical exam seems to be abnormal.

A computed tomography (CT) scan or magnetic resonance imaging (MRI) of the hypothalamus or pituitary gland may be done to look for any changes in these areas of the brain.

Early detection

Because of the possibility of intellectual disability in infants with hypothyroidism, every state in the United States tests newborns for hypothyroidism. If your baby was not born in a hospital, or if you believe your baby may not have been tested, talk to your doctor. Screening tests for hypothyroidism are not always accurate. Even if test results show no problem, watch your child for symptoms of hypothyroidism, such as poor appetite, not gaining weight, and dry skin.

Some doctors now recommend routine testing for people at risk for hypothyroidism, including:

  • People age 35 and older. The American Thyroid Association guidelines recommend that screening begin at age 35 and continue every 5 years thereafter.3
  • People with one or more close relatives who have or had hypothyroidism.
  • People with conditions associated with Hashimoto's thyroiditis, including Addison's disease, rheumatoid arthritis, pernicious anemia, and type 1 diabetes.
  • Pregnant women. In pregnant women known to have hypothyroidism, tests should be done at regular intervals to determine whether the dosage of thyroid hormone medicine is adequate.
  • Women who are having symptoms of hypothyroidism after pregnancy (postpartum hypothyroidism), such as depression, memory and concentration problems, or thyroid enlargement (goiter). Women who have had hypothyroidism during or after pregnancy should be retested if they become pregnant again.

Not all experts agree on whether to recommend widespread screening for hypothyroidism. Some groups say there is not enough evidence of benefit to recommend screening for everyone. But people who are at high risk—women older than 60 and anyone with a family history of thyroid disease or who has other autoimmune diseases—may want to be screened.4

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: August 07, 2012
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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