Lucentis May Treat Diabetes-Related Vision Loss
Studies Show Drug May Help Treat Patients With Diabetic Macular Edema
The Lucentis injections were generally safe, with overall side effects similar to those of sham injections, Boyer says.
However, cardiovascular problems, which included heart attacks, strokes, and deaths due to vascular conditions, affected 6% to 9% of patients given the higher dose of Lucentis compared with about 5% on sham.
High blood pressure was also more common with high-dose Lucentis: 2% to 3% vs. 0% to 1% with sham.
The studies were funded by Genentech. The company plans to submit the studies to the FDA later this year to seek approval for use of Lucentis in DME.
These findings were presented at a medical conference. They should be considered preliminary as they have not yet undergone the "peer review" process, in which outside experts scrutinize the data prior to publication in a medical journal.