By Robert Preidt
"Weight does not hamper the effectiveness of inhaled steroids in preschoolers, but this study provides clear evidence that maintaining a healthy weight in preschoolers may be an effective strategy for controlling asthma," Lang added. He directs Duke University School of Medicine's children's pulmonary function laboratory.
Nearly 10 percent of children in the United States have asthma, the study authors noted. The respiratory condition is a leading cause of emergency room visits and hospitalization among preschoolers.
For the new study, Lang's team looked at data from three clinical trials that took place between 2001 and 2015. Among more than 700 kids aged 2 to 5 years included in the analysis, one-third were overweight.
Some of the children had been randomly assigned to use inhalers daily while some used them occasionally. Others were given placebos while some received no treatment.
Overweight and obesity did not appear to reduce the effectiveness of corticosteroid inhalers in easing asthma symptoms, such as shortness of breath, coughing and chest pain.
But overweight kids -- those with a body mass index (BMI) above the 84th percentile -- who didn't use an inhaler had 70 percent more days with asthma symptoms than untreated kids with a healthy weight, the study found. BMI is a measurement of body fat based on height and weight.
The heavy children also had more full-blown asthma attacks, the researchers said.
"The impact of overweight and obesity on asthma has not been studied in the youngest asthma patients, and this finding is the opposite of what has been seen in older kids and adults who are overweight," Lang said in a Duke news release.
The findings were published this month in the Journal of Clinical Immunology.